Thrombin Structural and Functional Determinants as Therapeutic Targets
Rita Marchi & Mercedes López · International Blood Research & Reviews · 2016
Thrombin is the final serine protease generated during blood coagulation. This enzyme possesses a complex and fascinating structure composed not only by an active site but also by two positively charged patches, called anion binding exosites o simply exosites 1 and 2, as well as...
Open access
Research Article
10.9734/IBRR/2016/27562