Michael J. Adjabui

Identifying Minimum Effective Dose Under Heteroscedasticity

Michael J. Adjabui, Jakperik Dioggban & Irene D. Angbing · Asian Research Journal of Mathematics · 2021

We propose a stepwise confidence procedure for identifying minimum effective dose (MED) without multiplicity adjustment.Stepwise procedures strongly control the familywise error rate (FWER) which is a critical requirement for statistical methodologies in identification of MED. Th...

Open access Research Article 10.9734/arjom/2021/v17i430292

Nonparametric Stepwise Procedure for Identification of Maximum Safe Dose (MSD)

Michael J. Adjabui, Nathaniel K. Howard & Albert Luguterah · Asian Research Journal of Mathematics · 2017

In this article we consider identification of maximum safe dose (MSD) in a dose response study for distribution-free endpoints. Where the maximum safe dose is the highest dose level that does not exceed the median toxicity of the zero dose by a predetermined margin. A nonparametr...

Open access Research Article 10.9734/ARJOM/2017/36377