Recent Advances in the Synthesis of Piperazines: Focus on C–H Functionalization
Carolina Durand & Michal Szostak · Organics · 2021
Piperazine ranks as the third most common nitrogen heterocycle in drug discovery, and it is the key component of several blockbuster drugs, such as Imatinib (also marketed as Gleevec) or Sildenafil, sold as Viagra. Despite its wide use in medicinal chemistry, the structural diver...
Open access
Research Article
10.3390/org2040018