A Novel Decrease of Mrp3 Protein in Liver of β-Thalassemic Mouse
Mohammed Qaisiya, Lucia de Franceschi, Achille Iolascon, Claudio Tiribelli & Cristina Bellarosa · Journal of Advances in Medicine and Medical Research · 2016
Background: Hepatocytes have a fundamental system of efflux proteins that protect cells from toxic insults. Unconjugated bilirubin at higher concentration is toxic to cells and its intracellular accumulation is limited by the induction of efflux proteins such as Mrp3. In vivo stu...
Open access
Research Article
10.9734/BJMMR/2016/25139