Study of Isocitrate Dehydrogenase 1and 2 Mutations in Adult Egyptian Patients with Denovo Acute Myeloblastic Leukemia, Their Relation to Clinical Characteristics, FLT3/ITD and Nucleophosmin 1 Mutations and Impact on Treatment Outcome
Sherine Samir Barakat, Manal Abd Elsatar Elsorady, Mona Wagdy Ayad, Dalia Abd Elmoety Elneely & Fatma Mohamed Abd Elfatah · International Blood Research & Reviews · 2019
Background: Acute myeloid leukaemia (AML) is a malignancy that is heterogeneous in nature characterized by genetic abnormalities some of which are established in the diagnosis and prognosis of the disease. An additional role for alterations in epigenetic mechanisms has been also...
Open access
Research Article
10.9734/ibrr/2019/v9i230095