Midodrine Therapy in Cirrhosis with Refractory Ascites: Impact on Survival and Paracentesis Frequency Compared with Large-volume Paracentesis
Sahar Ahmed, Mohammed Omar Almosa, Nada Alhaj, Morad Marikh & Radiya Almosa · International Research Journal of Gastroenterology and Hepatology · 2026
Background: Refractory ascites is a major complication of cirrhosis with a 1-year survival rate of less than 50%. Large-volume paracentesis (LVP) is the standard treatment but does not improve survival and carries risks of circulatory dysfunction. Midodrine, an oral alpha-adrener...
Open access
Research Article
10.9734/irjgh/2026/v9i1146