Nahla A. M. Hamed

Expression of Glucocorticoid Receptor Isoforms (a, β, γ, and p) in Egyptian Primary Immune Thrombocytopenia Patients

Nahla A. M. Hamed, Mohamed Aldefrawy, Dalia Elneely, Omar Ghallab & Beatrice Jepngetich · International Blood Research & Reviews · 2015

Glucocorticoid (GC) resistance has been demonstrated in nearly 30% of primary immune thrombocytopenia (ITP) patients even managed with high dosages GC. The biological effects of GC are mainly mediated through activation of glucocorticoid receptors (GR). An insight into the molecu...

Open access Research Article 10.9734/IBRR/2015/20213

Preliminary Report on the Frequency of Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor-gamma Gene in Egyptian β-Thalassemia Major Patients

Mohamed El-Dafrawy, Nahla A. M. Hamed, Omar Ghallab, Dalia Elneely & Marwa Khalifa · International Blood Research & Reviews · 2016

Osteoporosis represents an important cause of morbidity in adult thalassemic patients. Peroxisome proliferator-activated receptor-γ (PPAR γ) is a master transcriptional regulator involved in expression of probably hundreds of genes. Recent studies have suggested that PPAR-γ plays...

Open access Research Article 10.9734/IBRR/2016/28458