Ngwoke, Chinaza Faith

From Bench to Bedside: Structural and Biological Barriers to Therapeutic Translation in Pancreatic Cancer

Reginald Oyortey, Tosin Abiodun Aderanti, Ngwoke, Chinaza Faith, Esosa Omoregie, Anointing Akindele, Salifu Faisal & Bethel Abioke Uchechukwu · Journal of Cancer and Tumor International · 2026

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, driven largely by KRAS mutations and profound therapeutic resistance. This review summarizes recent translational strategies aimed at bridging laboratory discoveries with clinical application, including...

Open access Research Article 10.9734/jcti/2026/v16i1345

Role of HLA Class I Molecule in Cancer: Implications for Cancer Immunotherapy

Josiah Stephen, Ikechukwu Kanu, Nwamaka Nneka Onyedum, Edibokun Theresa Orobator, Catherine Rono, Ngwoke, Chinaza Faith, Victor Omeiza David, Wonderful Oluwatoyin Anosike & Lawrence John AJutor · Journal of Cancer and Tumor International · 2025

HLA class I molecules are essential for presenting tumour antigens to cytotoxic T-cells, but their dysregulation in cancer enables immune evasion and limiting the efficacy of immunotherapies for cancer. The objective of this review is to explore the function of HLA class I change...

Open access Research Article 10.9734/jcti/2025/v15i3299