O. A. Olorunyomi

The Roles of Hydrogen Peroxide Exposure in the Toxic Aggregation of Alpha-synuclein and Translocation of DNA Methyltransferase-1 in Human Neuroblastoma Cell Model of Parkinson's Disease

O. A. Olorunyomi, S. G. Mafulul, K. M. Jiyil & D. P. Smith · Journal of Applied Life Sciences International · 2020

Background: Oxidative stress has been implicated in neuronal damage in Parkinson’s disease (PD). However, the specific roles of reactive oxygen species such as Hydrogen peroxide (H2O2) and Iron in the pathogenesis of PD especially, alpha-synuclein (α-Syn) aggregation and transloc...

Open access Research Article 10.9734/jalsi/2020/v23i430156

Chemical Changes during Thermal Processing of Unfermented and Fermented Red Kidney Beans (Phaseolus vulgaris) and effects on In Vitro Protein Digestibility

P. F. Wulam, M. K. Jiyil, C. E. Mafuyai, J. I. Oche, O. A. Olorunyomi & M. Silas · European Journal of Nutrition & Food Safety · 2021

Background: Legumes are outstanding sources of macronutrients, micronutrients, phytochemicals, as well as antinutritional factors. These components present a complex system enabling interactions with different components within food matrices. The interactions result in insoluble...

Open access Research Article 10.9734/ejnfs/2021/v13i330397

Antimicrobial Efficacy of Methanolic and Aqueous Extracts of Partially Purified Protein from Young and Matured Root of Guiera senegalensis (Moshi Medicine)

M. K. Jiyil, M. I. Shago, C. E. Mafuyai, M. Silas & O. A. Olorunyomi · International Journal of Biochemistry Research & Review · 2020

Background: Antibiotic resistance among pathogenic bacteria is increasing at an alarming rate leading to the need for traditional medicine as an alternative. Aim of the Study: The study aimed to evaluate the antimicrobial activity of methanolic and, aqueous extracts of partial pu...

Open access Research Article 10.9734/ijbcrr/2020/v29i530189