The Role of High-Dose Vitamin A on the Amygdala of Adult Male Wistar Rats Exposed to Toxic Doses of Methamphetamine
Ezejindu Damian NNABUIHE, Joshua Izuchukwu ABUGU, Enemuo IJEOMA, Okeke Somadina Nnamdi, Ogbuokiri Doris K, Okeke Henry Kachikwuru, Ekoh Augustine Alobu, Benedict Nzube Obinwa, Chinyere Elizabeth Eze, Nwaefulu Kester Eluemunor, Sobanke A. Omolara, Chidinma Ifeyinwa Mmaju, Okafor Anulika Jacinta, Chuka-Onwuokwu Ngozi Cynthia, Ejiogu Ikedichukwu Chibueze, Nwoko Sebastine Okechukwu, Wuraola Serah Nnaemeka, Ebi Victory Chinecherem, Agu Augustine Uchenna, Ugwu Augustus Uchenna, Nwodo Ndubuisi Francis, Elemuo Chukwuebuka Stanley, Agbai Johnson Ukwa, Muorah Chinecherem Onyekachi & Ozoemena Chiadikobi Lawrence · International Neuropsychiatric Disease Journal · 2026
The amygdala, a major limbic structure, regulates emotional response, anxiety, and memory formation. Methamphetamine is known to trigger oxidative stress and neurodegeneration, whereas vitamin A possesses potent antioxidant properties that may offer neuroprotection. This study ev...