Owokalade Princess Adekunbi

Oxidative Stress, Antioxidant Defense and Trace Element Alterations in Sickle Cell Disease during Vaso-Occlusive Crisis and Steady State

Temitope Oyewole Olusanya, Samuel Oluwatamilore Osubu, Toluwani Sikemioluwa Oyewo, Ayomide Motunrayo Banjo, Kamsiyochukwu Victoria Ife, Owokalade Princess Adekunbi & Abiodun Oluwasegun Adetola · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell disease (SCD) is associated with chronic haemolysis, inflammation and recurrent vaso-occlusive crises (VOC), with oxidative stress contributing to its pathophysiology. However, the interplay among oxidative stress, antioxidant defences and trace element st...