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P. Sankar Ganesh

Publications (9)

Attenuation of Quorum Sensing Controlled Virulence Factors and Biofilm Formation by Edible Fruit Extract of Coccinia indica against Pseudomonas aeruginosa

R. Shruthi Devi, P. Sankar Ganesh, A. S. Smiline Girija & J. Vijayashree Priyadharshini · Journal of Pharmaceutical Research International · 2021

Background: Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen that mainly infects immunocompromised individuals and patients with urinary tract infection and chronic infections of the respiratory pathways, including cystic fibrosis. Many quorum sensing (QS) c...

Open access Research Article 10.9734/jpri/2021/v33i47B33180

In silico Analysis of a Novel Peptide Vaccine against Hepatitis B Virus (HBV)

R. Sundar, P. Sankar Ganesh, A. S. Smiline Girija & J. Vijayashree Priyadharshini · Journal of Pharmaceutical Research International · 2021

Background : Hepatitis B is a potentially life-threatening liver infection caused by the Hepatitis B virus (HBV). It is a major global health problem and the most serious type of viral hepatitis. It can cause chronic liver disease and puts people at high risk of death from cirrho...

Open access Research Article 10.9734/jpri/2021/v33i47B33141

In vitro Evaluation of Antimicrobial Activity of Opuntia ficus-indica Seed Oil

Naz Fathima Raj Mohamed, R. V. Geetha & P. Sankar Ganesh · Journal of Pharmaceutical Research International · 2021

Introduction: Opuntia ficus-indica is a well adapted cactus to extreme climatic environments. In the usual diet and food industry, it is an interesting source of food ingredients. In general, the protective role of prickly pears has been due to their antioxidant components, pheno...

Open access Research Article 10.9734/jpri/2021/v33i47B33148

Detection of Immuno Dominant Peptides against pgaB of Acinetobacter baumannii

M. Indumathi, A. S. Smiline Girija, P. Sankar Ganesh & J. Vijayashree Priyadharsini · Journal of Pharmaceutical Research International · 2021

Background: Acinetobacter baumannii is a gram negative non-motile coccobacillus, which was considered as a low priority pathogen with low virulence. Recently, it was declared as the priority pathogen under the critical category of the most dangerous pathogen by WHO. Acinetobacter...

Open access Research Article 10.9734/jpri/2021/v33i47B33156

Virtual Screening to Identify the Protein Network Interaction of Berberine with Red Complex Pathogens

S. Abinaya, J. Vijayashree Priyadharsini, A. S. Smiline Girija & P. Sankar Ganesh · Journal of Pharmaceutical Research International · 2021

Introduction: Periodontal disease is an infection of the tissues that hold your teeth in place. It's typically caused by poor brushing and flossing habits that allow plaque, a sticky film of bacteria, to build up on the teeth and harden. Elimination of these pathogens from the si...

Open access Research Article 10.9734/jpri/2021/v33i47B33166

Virtual Screening to Identify the Protein Network Interactions of Triclosan with Streptococcus mutans and Enterococcus faecalis

T. K. Hariprasanth, J. Vijayashree Priyadharsini, A. S. Smiline Girija & P. Sankar Ganesh · Journal of Pharmaceutical Research International · 2021

Introduction: Triclosan is considered to be an important ingredient in toothpastes and mouth rinses. Several studies have reported contradictory results regarding the antimicrobial effect of triclosan. Hence, the present in silico study intends to identify the potential targets o...

Open access Research Article 10.9734/jpri/2021/v33i47B33169

Decoding the Genetic Alterations in Genes of Fibroblast Growth Factor Family and Their Possible Association with HNSCC

A. Akshaya, J. Vijayashree Priyadharsini, A. S. Smiline Girija, P. Sankar Ganesh & Nidhi Poddar · Journal of Pharmaceutical Research International · 2021

Introduction: HNSCC is a type of cancer in the oral and pharynx region. Several mutations/variations are observed in these cancer phenotypes. Fibroblast growth factor belongs to the family of heparin binding growth factors. FGFs are multifunctional proteins with a wide variety of...

Open access Research Article 10.9734/jpri/2021/v33i47B33172

Genetic Alterations in HSPA Family of Genes and their Putative Association with HNSCC

M. Laksita, J. Vijayashree Priyadharsini, A. S. Smiline Girija & P. Sankar Ganesh · Journal of Pharmaceutical Research International · 2021

Introduction: Head and neck squamous cell carcinoma (HNSCC) is an aggressive life-threatening disease associated with high mortality rates. Several genes related to stress response have been studied extensively to reveal their possible association with HNSCC. Members of the HSPA...

Open access Research Article 10.9734/jpri/2021/v33i47B33136

Virtual Screening to Identify the Protein Network Interaction of Triclosan in Red Complex Pathogens

N. V. Hemanth Ragav, J. Vijayashree Priyadharsini, A. S. Smiline Girija & P. Sankar Ganesh · Journal of Pharmaceutical Research International · 2021

Background: Antimicrobial drug resistance is the major problem encountered world-wide. Novel therapeutic leads have been identified and are regularly tested for their activity against microbial pathogens. Aim: To identify the protein network interactions of triclosan in red compl...

Open access Research Article 10.9734/jpri/2021/v33i47B33137