Evaluating the Genetic Landscape of (Plasmodium falciparum) PfKelch13 Gene Polymorphisms in Côte d'Ivoire Following a Decade of Artemisinin-based Combination Therapy
Coulibaly Baba, Aristide Berenger Ako, Serge Brice Assi, Tiacoh N’guessan Landry, Adji Gbessi Aka Eric, Brou Somela Marie Josée, Ehouman Marie Florence, Laeticia Gnamien, Coulibaly M’lanhoro Aristide, Béourou Sylvain, Bassinka Issiaka, Soumahoro Adama, Kadjo Florence, Menard Didier, Tanoh Mea Antoine, Penali Koné, Assanvo Simon-Pierre N’GUETTA & André Offianan Touré · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024
Introduction: Artemisinin-based combination therapies (ACTs) are the mainstay of malaria treatment globally. However, their effectiveness is threatened by the emergence of resistance in Plasmodium falciparum (P.f), particularly in Southeast Asia (SEA). Specific mutations within t...