Significant Lower Carboxylesterase Specific Activity in Meningiomas and Gliomas and Derived Primary Cell Culture Indicate Reduction in Anticancer Drug Metabolism
Prabha Muddobalaiah, Vasanthapuram Ravi & Narayana Swamy Ramachandra Swamy · International Research Journal of Oncology · 2021
Aims: Carboxylesterases (CE) convert carboxylic esters to alcohols and carboxylic acids. CE is a protective factor in the brain cells categorized as phase-I drug-metabolizing enzymes. Therefore we aim to find out the difference CE specific activity for Brain tumors as compared to...
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Research Article