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Pratibha Ramani

Publications (10)

Correlation of the Protein Expression of Salivary Cortisol, Serum Vitamin B12 and Interleukin 1 Beta in Patients with Recurrent Aphthous Stomatitis

R. Deepa Viswasini, Pratibha Ramani & J. Selvaraj · Journal of Pharmaceutical Research International · 2021

This study will help in determining which molecules participate in the ulceration with an integrated approach combining external and internal factors. Recurrent aphthous stomatitis (RAS) is a common condition affecting the oral mucosa. Clinically it is manifested through recurren...

Open access Research Article 10.9734/jpri/2021/v33i47A33003

The Association of Interleukin 1 Beta in Recurrent Aphthous Stomatitis – A Systematic Review

R. Deepa Viswasini, Pratibha Ramani & Gheena Sukumaran · Journal of Pharmaceutical Research International · 2021

Background: Recurrent aphthous stomatitis (RAS) is a chronic ulcerative disease with a complex aetiology and a strong immunological basis. The prototypical pro-inflammatory cytokine is interleukin-1 (IL-1). IL-1alpha and IL-1beta are the two subtypes of IL-1. The proinflammatory...

Open access Research Article 10.9734/jpri/2021/v33i46B32913

Cedarwood Oil as a Substitute for Xylene in Histopathological Laboratories – A Systematic Review

R. Deepa Viswasini, Pratibha Ramani & Abhilasha Ramasubramanian · Journal of Pharmaceutical Research International · 2021

Background: Xylene is an aromatic hydrocarbon that's extensively used as a deparaffinizing agent, and it's far extraordinarily biohazardous. It is proven to be the best chemical to be used in histopathological laboratories in spite of its carcinogenic potential. Aim: The aim of t...

Open access Research Article 10.9734/jpri/2021/v33i46A32895

Detection of Dental Caries Using Salivary Biomarkers – A Systematic Review

Krishnapriya Umashankar & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Saliva is a mixture of organic and inorganic components that comes in constant contact with the hard and soft tissues of the oral cavity. One of the most frequent disorders is dental caries, which is a multifactorial microbial disease of the tooth. Of which saliva pla...

Open access Research Article 10.9734/jpri/2021/v33i44A32598

Comparative Evaluation of Salivary Malondialdehyde Levels in Children with Different Caries Status- A Cross-Sectional Observational Study

Dhanalakshmi Ravikumar, Pratibha Ramani & R. Gayathri · Journal of Pharmaceutical Research International · 2021

Background and Objectives: Early childhood caries is a major public health problem especially in young children. ECC affects the quality of life of young children by affecting the chewing ability of children due to the development of pain and swelling, and this may indirectly aff...

Open access Research Article 10.9734/jpri/2021/v33i42A32395

Correlation of Streptococcus Mutans by 16SrRNA Gene Sequencing in Children with Different Caries Experience- A PCR Based Study

Dhanalakshmi Ravikumar, Pratibha Ramani, R. Gayathri & Selvaraj Jayaraman · Journal of Pharmaceutical Research International · 2021

Background and Objectives: Early Childhood Caries is considered as a common chronic disease in children. Since some research had concluded that children with higher levels of Streptococcus mutans are associated with a higher incidence of decayed, missing, and filled teeth, the pr...

Open access Research Article 10.9734/jpri/2021/v33i41B32341

Comparison of Salivary Protein Profile and Dietary Habits in Children With and Without Early Childhood Caries

Dhanalakshmi Ravikumar, Pratibha Ramani & R. Gayathri · Journal of Pharmaceutical Research International · 2021

Background and objectives: The purpose of this study was to evaluate the relationship between the total salivary protein concentration and dietary habits in Caries-free, Early childhood Caries and Severe Early Childhood Caries children. Materials and methods: The present study in...

Open access Research Article 10.9734/jpri/2021/v33i30A31622

Estimation of Salivary pH, Viscosity, Flow Rate in Children with and without Early Childhood Caries – An Observational Study

Dhanalakshmi Ravikumar, Pratibha Ramani & R. Gayathri · Journal of Pharmaceutical Research International · 2021

Background and Objectives: Early Childhood Caries (ECC) is a chronic disease of childhood affecting the primary dentition. It is also termed as nursing caries or baby bottle tooth decay. It has a multifactorial etiology and salivary parameters are considered as one of the importa...

Open access Research Article 10.9734/jpri/2021/v33i30A31614

Expression of ITG β-1, MMP9 and Vimentin in Oral Squamous Cell Carcinoma – A Real Time PCR Based Approach

Krishnapriya Umashankar, J. Selvaraj & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Oral Squamous Cell Carcinoma (OSCC) is the most common malignancies which accounts for 90% of oral cancer worldwide. The 5 year survival rate of OSCC is not more than 60% due to tumor metastasis and subsequent recurrence. Aim: To compare the gene expression of ITG β-1...

Open access Research Article 10.9734/jpri/2021/v33i44B32653

Comparative Evaluation on the Expression of Pi3 Kinase - AKT- mTOR Signalling Molecules in Oral Squamous Cell Carcinoma - A Real Time PCR Based Approach

Krishnapriya Umashankar, J. Selvaraj & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Oral squamous cell cancer (OSCC) develops as a result of the accumulation of many genetic mutations that are influenced by genetic predisposition. Upon acquisition of genetic predisposition, the precancerous cells will transform into malignant cells culminating into c...

Open access Research Article 10.9734/jpri/2021/v33i44A32605