Raphael Salles Ferreira Silva

Synthesis, Structural Elucidation and Trypanocidal Activity of 2-thiocyanil-1,4-naphthoquinone

Henrique José Coroado dos Santos, Igor Oliveira Maciel, Ana Carolina Ferreira de Albuquerque, Mauro Barbosa de Amorim, Luiz Dione Barbosa de Melo & Raphael Salles Ferreira Silva · Chemical Science International Journal · 2018

Aims: This work describes the synthesis of 2-thiocyanil-1,4-naphthoquinone and evaluates its trypanocidal activity. Study Design: Synthesis was carried under conventional heating, microwave and ultrasound irradiation. Molecular modeling was employed to assign correctly the thiocy...

Open access Research Article 10.9734/CSJI/2018/40288

Microwave Assisted Synthesis of Phenazines from β-Lapachones and Their Tuberculostatic Activity

Douglas Igor Santos de Oliveira, Lívia Fernandes do Amaral, Maria Cristina Silveira Lourenço, Nelilma Correia Romeiro, Vítor Won-Held Rabelo & Raphael Salles Ferreira Silva · Chemical Science International Journal · 2017

Aims: The study aimed to investigate de synthesis of phenazines by microwave assisted reactions and evaluate the tuberculostatic activity. Study Design: The method developed in the study is an alternative for the method described in the literature employing acetic acid, an effici...

Open access Research Article 10.9734/CSJI/2017/30943