Tumor necrosis factor alpha (TNF-α), also called cachectin or cachexin, is a naturally occurring cytokine produced by activated macrophages and monocytes, and to a smaller scale by T-lymphocytes, B-lymphocytes, fibroblasts and astrocytes. It has both inflammatory and immunomodula...
Brian Mark Churchill, Charu Gautam, Saket Ghaisas, Rashna Cama, Craig Davis, Bela Shah, Kiran Godse, Yogesh Marfatia, Ramesh Bhat, Sushil Pande & Sonja Vanwye·Asian Journal of Research in Dermatological Science·2022
Psoriasis is a non-communicable disease characterized by inflammation involving cutaneous T cells, dendritic cells, and keratinocytes. Release of cytokines leads to keratinocyte hyperproliferation and scaly plaques, and other manifestations of the disease including psoriatic arth...