Association between TP53 and MDM2 Gene Polymorphisms and Risk of Hepatocellular Carcinoma in Hepatitis C Virus among Egyptian Populations
Ahmed Mohamed Zaky, Shaden Muawia Hanafy, Magdy Mamdouh El- Bordiny & Reham Abdel Haleem Abu El- Wafa · Asian Journal of Research in Biochemistry · 2020
Background: The Murine double minute 2 (MDM2) gene is overexpressed in several human tumors. The oncogenic potential of MDM2 is partially explained by inhibition of the activity of the tumor suppressor protein P53 (negative regulator of the P53 tumor suppressor protein). A single...
Open access
Research Article
10.9734/ajrb/2020/v7i430159