Renato C. S. Lessa

Synthetic Organic Molecules as Metallic Corrosion Inhibitors: General Aspects and Trends

Renato C. S. Lessa · Organics · 2023

Organic molecules are gaining special attention over the last years in the corrosion area thanks to their general low achievable cytotoxicity, structural versatility, and environmentally friendly obtainment methods. Under those approaches, synthetic organic motifs have attracted...

Open access Research Article 10.3390/org4020019

Ten Years Milestones in Xanthine Oxidase Inhibitors Discovery: Febuxostat-Based Inhibitors Trends, Bifunctional Derivatives, and Automatized Screening Assays

Miguel F. S. de Abreu, Camila A. Wegermann, Millena S. Ceroullo, Isabella G. M. Sant’Anna & Renato C. S. Lessa · Organics · 2022

Xanthine oxidase (XO) is an enzyme involved in the oxidative process of hypoxanthine and xanthine to uric acid (UA). This process also produces reactive oxygen species (ROS) as byproducts. Both UA and ROS are dangerous for human health, and some health conditions trigger upregula...

Open access Research Article 10.3390/org3040026