Richard Adedamola Ajike

Sequential Administration of Febuxostat, Amlodipine and Vitamin E Attenuate Oxidative Stress and Improve Spermatogenesis in Testicular Ischemia Reperfusion Injury in Wistar Rats

Richard Adedamola Ajike, Oladele Ayobami Afolabi, Ayodeji Folorunsho Ajayi, Olajumoke Deborah Ogunleye, Waidi Adeoye Saka, Olusola Bamidele & Oluwaseun Samuel Hezekiah · International Journal of Biochemistry Research & Review · 2024

This study investigated the effects of sequential administration of febuxostat, amlodipine, and vitamin E on oxidative stress and spermatogenesis following testicular ischemia-reperfusion injury (TIRI) in Wistar rats. Ninety male rats (120-150 g) were divided into 9 groups (n=10...

Open access Research Article 10.9734/ijbcrr/2024/v33i6894

Effect of Curcumin on Cognitive Impairment in Aged Female Wistar Rats Subjected to Intestinal Ischemia-reperfusion Injury

Opeyemi Sodiq Hammed, Oladele Ayobami Afolabi, Richard Adedamola Ajike, Babatunde Adebola Alabi, Olubunmi Simeone Oyekunle, Waidi Adeoye Saka, Janet Oreoluwa Adedeji, Bamidele Oluwole Olusola & Olajumoke Deborah Ogunleye · Journal of Applied Life Sciences International · 2025

Cognitive deficit, more common with age, it affects memory and cognitive functions. Intestinal ischemia-reperfusion injury (IIRI) causes systemic inflammation that can damage the brain, particularly the hippocampus. Curcumin, an active ingredient found in turmeric have neuroprote...

Open access Research Article 10.9734/jalsi/2025/v28i1676

Cardiac Effects of Combined Lead Exposure and Chronic Restraint Stress: Alterations in Biomarkers and Myocardial Health

Gbenga Opeyemi Owolabi, Omorolade Oluwatobi Osinloye, Ridwanullahi Adejumo, Ibukunoluwa Victor Fayemi & Richard Adedamola Ajike · Asian Journal of Advanced Research and Reports · 2024

Lead is a toxic metal and an environmental pollutant that has been associated with an increased incidence of cardiovascular diseases while restraint stress is a psychological stress model that can also potentially induce deleterious effects on cardiac functions. The aim of this s...

Open access Research Article 10.9734/ajarr/2024/v18i12806