Rupali Ghosh

siRNA: A Comprehensive Review of Marketed Products till August 2022

Rupali Ghosh, Md. Iqbal Hossain Nayan & Tirtha Nandi · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Small interference RNA (siRNA) is a double-stranded RNA of 21~25 nucleotides. siRNA functions using a natural phenomenon known as RNA interference (RNAi), a gene silencing mechanism. Hypothetically, siRNA can target and regulate the expression of any disease-related gene in a seq...

Open access Research Article 10.9734/jamps/2023/v25i1596

Common Approaches of Cytochrome P450 (CYP) Induction Assays

Rupali Ghosh, Md. Iqbal Hossain Nayan, Mehedi Mala Mitu & Tirtha Nandi · International Blood Research & Reviews · 2023

The induction of enzymes is a defensive mechanism for some xenobiotics, but it may alter the drug's safety and efficacy by altering the activity of metabolic enzymes. One of the major families of enzymes involved in phase I metabolism is Cytochrome P450 (CYP) enzymes which may ge...

Open access Research Article 10.9734/ibrr/2023/v14i1297