Rutesh H. Dave

Solubility Enhancement of a BCS Class II Drug Using Granulated Fumed Silica as an Adsorbent

Sawani D. Talekar & Rutesh H. Dave · Journal of Pharmaceutical Research International · 2017

Aim: The aim of this study was to improve solubility and dissolution characteristics of Ibuprofen using granulated fumed silica (Aeroperl®300) as a carrier. Methods: Ibuprofen-silica complex was prepared by solvent evaporation technique using ethanol as the solvent. Formulation I...

Open access Research Article 10.9734/JPRI/2017/36872

A Review on Tablet Scoring: Background, History and Current Regulatory Considerations

Maitri R. Trivedi, Hardikkumar H. Patel & Rutesh H. Dave · Journal of Pharmaceutical Research International · 2018

Tablet splitting or breaking of tablets into multiple strengths has been a common practice across the world. Splitting of tablet offers various advantages such as dose flexibility and ease of swallowing in different population including geriatric and pediatric patients (wide pati...

Open access Research Article 10.9734/JPRI/2017/39027