Saleem H. Aladaileh

Renoprotective Effect of Formononetin against Cyclophosphamide-Induced Oxidative Stress and Inflammation in Rat Kidney

Saleem H. Aladaileh, Farhan K. Al-Swailmi, Mohammad H. Abukhalil & Mohammed H. Shalayel · Journal of Pharmaceutical Research International · 2021

Aims: Cyclophosphamide (CP) is a broad-spectrum chemotherapy agent available to treat various malignancies; however, its nephrotoxicity limits its clinical use. Formononetin (FOR) is a bioactive isoflavone with encouraging biological activities. The current study explored and elu...

Open access Research Article 10.9734/jpri/2021/v33i231144

Vitamin D is a New Promising Inhibitor to the Main Protease (Mpro) of COVID-19 by Molecular Docking

Ghassab M. Al-Mazaideh, Mohammed H. Shalayel, Farhan K. Al-Swailmi & Saleem H. Aladaileh · Journal of Pharmaceutical Research International · 2021

In this study, vitamin D has shown greater efficacy of binding with Mpro of COVID-19 compared to the recently recommended drugs. The docking study was simulated to streamline interaction effects of Vitamin D, Remdesivir, Chloroquine, Hydroxychloroquine, Aspirin, and Azithromycin...

Open access Research Article 10.9734/jpri/2021/v33i29B31603