Sameer E. Alharthi

Potentiation of Cisplatin Activity in Colorectal Cancer Cells by Lovastatin

Sameer E. Alharthi · Journal of Pharmaceutical Research International · 2019

Cisplatin (CIS) is an anticancer drugs used in the treatment of several solid tumors with nephrotoxicity as its main toxic effect. The current study was directed to assess the role of hypolipidemic drug (lovastatin) on sensitization of human colorectal cancer cells (HCT -116) to...

Open access Research Article 10.9734/jpri/2019/v28i130191

Cardioprotective Effect of Marine Astaxanthin on Doxorubicin-Induced Cardiotoxicity in Normal Rats

Ali A. AlQahtani, Abdel-Moneim M. Osman, Zoheir A. Damanhouri, Huda M. Al-Kreathy, Hamdan S. Al-Malky, Wafaa S. Ramadan, Sameer E. Alharthi & Fatemah O. Kamel · Journal of Pharmaceutical Research International · 2019

Background: Doxorubicin (DOX) is an effective antineoplastic drug indicated to treat many cancerous diseases but its clinical usefulness is limited by many side effects. The main and the most serious one is DOX induced cardiotoxicity. Many strategies have been tried to minimize t...

Open access Research Article 10.9734/jpri/2019/v27i330170