Samuel Adavba

Human Homeobox Genes in Development and Cancer

Samuel Adavba · International Research Journal of Oncology · 2023

The homeobox (HOX) genes encode highly conserved, homeodomain-containing transcriptional factors that play a central role in embryonic development and the maintenance of cellular identity crucial to the differentiation of adult stem cells. Implicitly, the pathophysiological relev...

Open access Research Article

Molecular Genetics of Gucy2d Gene among Patients with Leber Congenital Amaurosis Attending National Eye Center Kaduna

Farida Sagir Yaro, Yahaya Abdullahi Umar, Deborah Madi Dibal, Nkechi E. Egbe, Zahra’u Umar, Firdausi Aliyu, Samuel Adavba, Muhammad I. Tahir, Aliyu Adamu & Zakiya Mahmood · Asian Journal of Biotechnology and Genetic Engineering · 2023

Leber congenital amaurosis (LCA) is a clinically and genetically heterogeneous disease that presents with the autosomal recessive pattern of inheritance. There are about 19 genes responsible for the pathogenic cause of the disease, with mutations in a few of the genes recorded. T...

Open access Research Article