Lectin-Like Oxidized LDL Receptor 1 Mediates the Uptake of the C-Terminal Domain of Hsp70 (A Promising Immune Adjuvant Molecule) and Antigen Peptide Complexes
Miyuki Kumano-Kuramochi, Shoko Kajiwara, Takashi Minowa & Sachiko Machida · International Journal of Biochemistry Research & Review · 2014
Aims: Extracellular heat shock protein 70 (Hsp70) is an adjuvant molecule that stimulates the immune system. The C-terminal domain of Hsp70 (C70), without the ATPase domain, is sufficient for antigen cross-presentation. However, the mechanism by which the receptor mediates the u...
Open access
Research Article
10.9734/IJBCRR/2014/8699