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Sita Kumari Karanam

Publications (3)

Advances in CRISPR-Cas9 Genome Editing: Mechanisms, Variants, Delivery Systems, and Biomedical Applications

Raja Sekhar Yeluri, Navya Sri Gorli & Sita Kumari Karanam · Asian Journal of Biotechnology and Genetic Engineering · 2025

The CRISPR-Cas9 technology and related programmable nucleases have transformed genome editing by enabling precise and targeted DNA modifications in eukaryotic cells. Compared with earlier tools such as zinc-finger nucleases and TALENs, Cas9 provides higher efficiency and programm...

Open access Research Article 10.9734/ajbge/2025/v8i2172

Postbiotics as Emerging Functional Biotics: Antimicrobial Potential, Production Strategies, and Mechanistic Insights

Asritha Datla, Jahnavi Ponnaganti, Vandana Setti, Bhargavi Kalisetti, Munna Patro, Sita Kumari Karanam & Ramaiah Maddi · Asian Journal of Biotechnology and Genetic Engineering · 2026

Background: Postbiotics have recently emerged as a promising category of functional biotics derived from microbial fermentation. Unlike probiotics, postbiotics consist of non-viable microbial cells, metabolites, and structural components that exert biological effects without requ...

Open access Research Article 10.9734/ajbge/2026/v9i1181

Biomedical Implant Materials in Transition: Recent Developments, Clinical Applications and Future Perspectives

Ampolu Vimalavathi, Varun Varma Mudunuru, Sunkari Pallavi, Gorle Alekhya, Pedamajji Hema, Pudivalasa Vijayakumari, Shaik. Yasmin, Sita Kumari Karanam & Ramaiah Maddi · Asian Journal of Biotechnology and Genetic Engineering · 2026

Biomedical implants increasingly depend on materials engineered not only for load bearing or structural replacement, but also for controlled interactions with bone, soft tissue, blood, immune cells, microorganisms and diagnostic or therapeutic systems. This critical narrative rev...

Open access Research Article 10.9734/ajbge/2026/v9i2201