Sophia Massesine Pimentel

Integrative Transcriptomic and Network Pharmacology Analysis Reveals Candidate Molecular Associations and Hypothesis-Generating Drug-Gene Relationships in Major Depressive Disorder

Laura Gomes Libório, Sophia Massesine Pimentel & Sara Laíse Cordeiro · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Aims: To characterize transcriptomic alterations associated with major depressive disorder (MDD) in postmortem human brain tissue and integrate differential gene-expression findings with protein-protein interaction, functional-enrichment, and drug-gene interaction analyses. Study...