Numerous studies have been carried out on the structure of 2,3-dihydro-1H-perimidine substituted as compounds with various biological activities. Researchers have found that these compounds exhibit characteristics potentially useful in medicinal chemistry research and have many t...
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Research Article10.9734/CSJI/2021/v30i430227
This reactivity study was performed on seven molecules of a 2,3-dihydro-1H-perimidine series using density functional theory at the B3LYP / 6-311 G (d, p) level. Calculation of the dipole moment showed that compound 4 is more soluble in aqueous medium. The study of frontier molec...
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Research Article10.9734/irjpac/2022/v23i130451
In order to study the Quantitative Structure Activity Relationship (QSAR) against protein tyrosine phosphatase 1B and descriptors, we used a series of fourteen (14) molecules derived from perimidine. The compounds were optimized at the computational level B3LYP / 6-31 G (d, p), t...
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Research Article10.9734/irjpac/2021/v22i830426
Niaré Adama, Attia Yapo John Alex, Djako Akassa Marius Bernard, Kambiré Sobamfou Marius, Dembélé Georges Stéphane, Kouadio Assandé Moise, Koné Mamadou Guy-Richard, Yves Kily Hervé Fagnidi & Soro Doh·Asian Journal of Chemical Sciences·2025
Malaria, although a curable disease, continues to be the most important infectious disease in terms of incidence and mortality worldwide. It is a potentially fatal disease caused by parasites transmitted to people through the bites of infected female Anopheles mosquitoes. This di...
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Research Article10.9734/ajocs/2025/v15i1352