Sudan Ye

Physiological Indicators of Paeoniflorin and Caffeine in Modulating the Motility of Caenorhabditis elegans Via Adenosine Receptor

Wenjie Nie, Shuning Hu, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2025

Aims: Paeoniflorin exhibits a broad range of in vitro and in vivo pharmacological effects. However, its potential as a drug targeting adenosine receptors remains largely unexplored. Methodology: In this study, the wild-type N2 strain and the Ador-1 gene knockout EG6890 strain of...

Open access Research Article 10.9734/arrb/2025/v40i42219

Physiological Indicators of Adenosine and Salidroside Regulating the Motor Behavior in a Caenorhabditis elegans Model Via Ador-1 Adenosine Receptor

Yingcheng Yang, Shuning Hu, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2025

Aims: Adenosine and salidroside exert both preventive and therapeutic effects on neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. However, the mechanism is unclear. Methodology: N2 wild-type and EG6890 (Ador-1 gene knockout) Caenorhabditis elegans were...

Open access Research Article 10.9734/arrb/2025/v40i32211

Lactic Acid Inhibits the Cytotoxicity of NK-92 Cells via Activating the Lactate Receptor GPR81

Yaobiao Huang, Wenjie Nie, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2023

Aims: Lactate acid functions as not only an energy source but a signaling molecule through the lactate receptor GPR81 under physiological conditions. However, the pathological role of lactic acid in the tumor microenvironment remains unclear, particularly for immune cells. Method...

Open access Research Article 10.9734/arrb/2023/v38i330573