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Süleyman Gökçe

Publications (2)

Development and Validation of UPLC-MS / MS Method for Obtaining Favipiravir Tablet Dosage form and Evaluation of its Behavior Under forced Conditions

Süleyman Gökçe, Ayşen Höl & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2021

Aims: Favipiravir (FVP) is a drug developed against RNA viruses. It is a drug that is used actively in the treatment of coronavirus. In vitro and in vivo investigations have shown that it inhibits the virus. In this study, a recovery study of tablet formulations was carried out b...

Open access Research Article 10.9734/jpri/2021/v33i56A33895

Determination of pKa and Degradation Products of the Mutated BRAF Inhibitor Vemurafenib and UPLC Assay in Human Urine

Senem Şanli, Ayşe Özdemir, Gülşen Güven & Süleyman Gökçe · Journal of Pharmaceutical Research International · 2020

In this study, the pKa value of vemurafenib was determined by the dependence of the retention factor on the pH of the mobile phase. The change of pKa in the different acetonitrile fraction ranging between 57.5 and 62.5% (v/v) was studied by using an LC-UV method. Additionally, a...

Open access Research Article 10.9734/jpri/2020/v32i3630986