Post-Translational Modifications of α-Synuclein: Drivers of Aggregation and Synucleinopathy Pathogenesis: A Systematic Review
Swagata Sarkar, Anwesha Bannerjee, Shrayoshree Putatunda, Soni Kumari & Amlanjyoti Dhar · Asian Journal of Research and Reports in Neurology · 2026
Aims: This systematic review aimed to critically evaluate the influence of post-translational modifications (PTMs) on α-synuclein structure, aggregation, and toxicity, and to clarify their relevance to the pathogenesis of Parkinson’s disease, dementia with Lewy bodies, and multip...