The Gut–NET–ICB Axis: Microbial Metabolite-Mediated Regulation of NETosis and Implications for Cancer Immunotherapy
Islam Ariremako Jimoh, TOBECHI BRENDAN NNANNA, TAIWO MICHEAL OLUMUJI, Paul Onyekachi Ukegbu, Michael Sewanu Hungbo & Kanime Hussaini · Asian Journal of Immunology · 2025
Background: Immune checkpoint blockade (ICB) has transformed oncology, but its efficacy is limited by primary and acquired resistance. The gut microbiome is a established determinant of ICB response, while neutrophil extracellular traps (NETs) have recently emerged as key mediato...
Open access
Research Article
10.9734/aji/2025/v8i1177