Role of the Trp-disulfide Triads in the UV Light Induced Degradation of a Monoclonal Antibody scFv
Eszter Illyés, Stephanie Staelens, Vanhooren ., Hans Deckmyn, Ignace Hanssens & Zsuzsa Majer · International Journal of Biochemistry Research & Review · 2014
Aims: Proteins are targets for photodegradation due to absorption of incident light by endogenous chromophores, e.g aromatic side chains. In this work we study the role of Trp-disulfide triads in the light induced loss of immunoglobulin activity. Study Design: We investigated a s...
Open access
Research Article
10.9734/IJBCRR/2014/8453