Yaobiao Huang

Lactic Acid Inhibits the Cytotoxicity of NK-92 Cells via Activating the Lactate Receptor GPR81

Yaobiao Huang, Wenjie Nie, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2023

Aims: Lactate acid functions as not only an energy source but a signaling molecule through the lactate receptor GPR81 under physiological conditions. However, the pathological role of lactic acid in the tumor microenvironment remains unclear, particularly for immune cells. Method...

Open access Research Article 10.9734/arrb/2023/v38i330573

In vitro Assessment of Polysaccharides Immunoregulatory Effects on CD3+CD56+ NKT-like Cells

Minghao Lu, Yaobiao Huang, Lianyang Yang & Chun Chen · Annual Research & Review in Biology · 2021

Aims: Polysaccharides have shown efficacy in a broad range of applications, especially in immune regulation. However, there are only few effective methods available to evaluate and compare the immunoregulatory properties of the different polysaccharides in vitro. To screen string...

Open access Research Article 10.9734/arrb/2021/v36i430365