Yoji Kyotani

Endothelin-1 (1-31) Causes the Migration of Vascular Smooth Muscle Cells through Endothelin ETA Receptor

Yoji Kyotani, Jing Zhao, Kentaro Ozawa, Takahiko Nakagawa, Francesco Bolstad & Masanori Yoshizumi · British Journal of Pharmaceutical Research · 2016

Endothelin-1 (ET-1) is predominantly expressed in endothelial cells to modulate physiological actions, such as vasoconstriction and cell proliferation. It acts as an autocrine and paracrine factor, and has been reported to be found in increased levels in the blood of patients wit...