Zaccheaus Awortu Jeremiah

Haematological Consequences of Systemic Inflammation: A Critical Narrative Review of Pathophysiology, Clinical Manifestations, Biomarkers and Therapeutic Implications

Zaccheaus Awortu Jeremiah & Joyce Ezekiel Etura · International Blood Research & Reviews · 2026

Inflammation is inseparable from blood-cell biology: circulating cells detect inflammatory cues, bone-marrow progenitors alter lineage output, erythroid iron supply is actively restricted, and haemostatic pathways can be recruited as components of host defence. Yet the expression...

Open access Research Article 10.9734/ibrr/2026/v17i4396

Serum Concentrations of VCAM-1, P-Selectin, and ICAM-1 are Downregulated during CPDA-1 Storage of Whole Blood

Augustine Okereke Abani, Stella Urekweru Ken-Ezihuo & Zaccheaus Awortu Jeremiah · International Blood Research & Reviews · 2026

Background: Storage of whole blood is accompanied by biochemical and cellular changes that may alter soluble adhesion molecules. This study evaluated serum concentrations of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin dur...

Open access Research Article 10.9734/ibrr/2026/v17i4400

Translating Vascular Biology into Clinical Benefit: A Critical Narrative Review of Sickle Cell Thromboinflammation in West Africa

Erens Spiff Ekprikpo, Stella Urekweru Ken-Ezihuo, Beauty Eruchi Echonwere-uwikor & Zaccheaus Awortu Jeremiah · International Blood Research & Reviews · 2026

Sickle cell disease is a systemic vasculopathy in which intravascular haemolysis, endothelial activation, leukocyte and platelet recruitment, and coagulation activation operate as a single self-reinforcing process now commonly described as thromboinflammation. Most of the mechani...

Open access Research Article 10.9734/ibrr/2026/v17i4399