Ziaullah M. Sain

Computational Screening of Natural Compounds for the Discovery of Potential Aromatase Inhibitors: A Promising Therapy for Estrogen-Dependent Breast Cancer

Misbahuddin M. Rafeeq, Ziaullah M. Sain, Norah A. Alturki, Ahmad Alzamami, Saeed A. Asiri, Mutaib M. Mashraqi, Amany I. Alqosaibi, Mashael M. Alnamshan, Abdulrahman Almutairi, Abdulkhaliq Munawir Alanazi & Qamre Alam · Journal of Pharmaceutical Research International · 2021

Aromatase plays a significant role in the progression of estrogen receptor-positive (ER-positive) breast cancer. The adverse side effects of currently used aromatase inhibitors (AIs) necessitate the development of new AIs that are more active, selective, and less toxic. This stud...