Aims: To report an atypical phenotypic presentation of Lesch-Nyhan syndrome (LNS) revealed by isolated generalised hypotonia and growth retardation in the absence of the classical neurological and behavioural features, and to emphasise the importance of systematic serum uric acid...
Open access
Research Article10.9734/ajpr/2026/v16i9587
Chronic malabsorption in early childhood is commonly associated with gastrointestinal disorders such as coeliac disease, but overlapping clinical features may delay recognition of other systemic causes, including cystic fibrosis. This case report describes a 2½-year-old boy who p...
Open access
Research Article10.9734/ajpr/2026/v16i9571
Achondroplasia arises almost invariably from a single recurrent gain-of-function variant in the gene encoding fibroblast growth factor receptor 3, and has therefore become a reference case for genotype-directed drug development in paediatric rare disease. Within five years the fi...
Open access
Research Article10.9734/ajpr/2026/v16i9568
Aims: This study aimed to compare accelerometer-measured physical activity and sedentary time between children with and without disabilities and to examine socio-ecological correlates stratified by disability status. Study Design: A cross-sectional secondary analysis of a populat...
Open access
Research Article10.9734/ajpr/2026/v16i9569
Ashraf T. Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Shayma Ahmed, Khaled A. Siddiq, Mohammed Qusad & Mohamed Alkalaf·Asian Journal of Pediatric Research·2026
Hookworm infection remains one of the most common chronic parasitic conditions of childhood in low-resource settings, and growth impairment is routinely listed among its consequences. The evidence supporting that claim is weaker and more heterogeneous than programmatic language i...
Open access
Research Article10.9734/ajpr/2026/v16i9570
Background: The BAV–VSD–PDA complex, presenting with severe symptomatic AR and severe LVD in a paediatric patient younger than 10 years, is a very uncommon complex congenital structural heart defect. Aim: This report aims to highlight surgical management strategies and a successf...
Open access
Research Article10.9734/ajpr/2026/v16i9567
Lere P. Oluwadare, Sampson C. Aliozor, Adebowale T. Odunafolabi, Samuel T. Oladejo, Adedamola A. Dada, Joshua O. Awofeso, Pauline K. Akowundu & Oluwapelumi O. Olusoga-Peters·Asian Journal of Pediatric Research·2026
Background: About a third of the global burden of disease is estimated to be surgical. Surgical conditions are common in the paediatric age group, making paediatric surgical care an important component of global health. The study aimed to describe the spectrum of paediatric surgi...
Open access
Research Article10.9734/ajpr/2026/v16i9566
Background: Preterm neonates are vulnerable to respiratory, infectious, metabolic, gastrointestinal, neurological and cardiovascular complications, and local data are needed to guide neonatal service planning. Objective: To determine the frequency and describe the clinical charac...
Open access
Research Article10.9734/ajpr/2026/v16i9565
Circulating fetoplacental nucleic acids have transformed prenatal medicine within a single generation, and screening based on cell-free DNA (cfDNA) is now offered routinely in many health systems. The field is moving quickly from the detection of whole-chromosome aneuploidy towar...
Open access
Research Article10.9734/ajpr/2026/v16i9564
Severe childhood epilepsy syndromes, encompassing the developmental and epileptic encephalopathies together with related drug-resistant electroclinical constellations, remain among the most challenging conditions in paediatric neurology. They combine frequent, treatment-resistant...
Open access
Research Article10.9734/ajpr/2026/v16i9563