Blood group typing has changed more in the past three decades than in the preceding hundred years. What began as an exercise in observing agglutination reactions has become, increasingly, an exercise in reading DNA: a shift from describing antigens as they appear on the red cell...
Open access
Research Article10.9734/ibrr/2026/v17i4391
Kouamé Norman Isaac Klébair, Kamara Ismael, Assohou Hiabba Emmanuela, Atseye Chiadon Carele Charlene, Kouadio Emmanuel, Boidy Kouakou & Gustave Kouassi Koffi·International Blood Research & Reviews·2026
Spontaneous non-traumatic epidural haematoma is an uncommon but potentially fatal neurological complication of sickle cell disease. This case report describes a 13-year-old girl with homozygous sickle cell disease who was admitted with a non-febrile vaso-occlusive crisis after in...
Open access
Research Article10.9734/ibrr/2026/v17i4390
Chiemelie Raluchukwu Onwasigwe, Michael Chidiebele Egolum, Angela Ogechukwu Ugwu & Hector Okechukwu Obianyido·International Blood Research & Reviews·2026
Background: Non-Hodgkin lymphoma is a heterogeneous group of lymphoid malignancies with variable clinical behaviour and treatment outcomes. In resource-constrained settings, limited access to advanced prognostic investigations increases the need for simple biomarkers. This study...
Open access
Research Article10.9734/ibrr/2026/v17i3389
Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi·International Blood Research & Reviews·2026
Hemoglobinopathies (e.g., HbS, HbC, HbF) are the most common single-gene disorders worldwide, especially in sub-Saharan Africa. Beyond affecting red blood cells and oxygen transport, they significantly disrupt blood clotting (hemostasis) and blood flow properties (haemorheology)....
Open access
Research Article10.9734/ibrr/2026/v17i3388
Ndudi Dibigbo–Ibeaji, Sylvia Ifeoma Obu, Gabriel Obisike Obu, Samuel Okwuchukwu Ilikannu, Akinkunmi Ibukun Jacob & Ezunu Ngozi Esther·International Blood Research & Reviews·2026
Background: Pancytopenia reflects a failure of normal hematopoiesis or excessive destruction or sequestration of blood cells and is frequently associated with significant morbidity and mortality if not promptly identified and managed. Despite growing global recognition of the sys...
Open access
Research Article10.9734/ibrr/2026/v17i3385
Background: Hypertension is a leading modifiable risk factor for cardiovascular disease, and midlife is a critical period when adverse systolic blood pressure (SBP) trajectories emerge. We estimated nationally representative associations between SBP and demographic, socioeconomic...
Open access
Research Article10.9734/ibrr/2026/v17i3386
Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi·International Blood Research & Reviews·2026
Reference intervals, the statistically defined ranges of physiological parameter values expected in a healthy reference population, constitute a cornerstone of clinical laboratory medicine. In haemorheology, reference intervals for whole blood viscosity, plasma viscosity, erythro...
Open access
Research Article10.9734/ibrr/2026/v17i3387
Background: Maternal alloimmunisation against the RhD antigen remains a preventable cause of haemolytic disease of the foetus and newborn (HDFN), a condition responsible for substantial perinatal morbidity and mortality in resource-limited settings. Population-specific data on Rh...
Open access
Research Article10.9734/ibrr/2026/v17i3384
Blood group antigen variability has significant implications for transfusion safety and prevention of alloimmunization, particularly in multi-ethnic populations where antigen expression may differ. This study investigated the distribution of Kell and Duffy blood group antigens am...
Open access
Research Article10.9734/ibrr/2026/v17i2383
Background: Hydroxyurea is the most accessible disease-modifying therapy for sickle cell disease (SCD), but in many low- and middle-income countries its real-world benefit is constrained by gaps in awareness, uptake, continuity, and adherence. We analyzed the full hydroxyurea pat...
Open access
Research Article10.9734/ibrr/2026/v17i2382