Aims: To isolate and evaluate the biological activities of the compounds present in the roots of Ochna serrulata. Study Design: Laboratory isolation of compounds by using various chromatographic methods, and cytotoxicity and antimalarial evaluations of the isolated compounds. Pl...
Open access
Research Article10.9734/IRJPAC/2018/42440
A simple and efficient one-pot three-component synthesis of Mannich type reaction has been developed using recyclable Fe+3-montmorillonite K10 (Fe+3@K10) under solvent-free condition. The reaction of aromatic aldehydes, aromatic anilines and aryl ketones produced β-amino carbony...
Open access
Research Article10.9734/IRJPAC/2018/41983
Aspartame (ASP) is an Artificial Sweetener used to substitute sugar which was said to cause some health disorders. It is about 200 times sweeter than sugar, with almost the same calorie value of 17 KJ per gram; a smaller quantity then, provides the same sweetness as...
Open access
Research Article10.9734/IRJPAC/2018/41441
A series of alumina and silica supported molybdenum oxide catalysts were prepared using ammonium heptamolybdate at different loading levels (5 – 20 wt% of molybdenum oxide) by the impregnating method. The total acidity of the solid catalysts was measured by means of potentiometri...
Open access
Research Article10.9734/IRJPAC/2018/41667
A hetero-catalyst, Co2+ and Zn2+ impregnated Bentonite-Chitosan composite (Co2+-BCC and Zn2+-BCC) has been developed separately and characterized using scanning electron microscope (SEM), for the synthesis of a different class of nitrogen containing 5 and 6 membered heterocyclic...
Open access
Research Article10.9734/IRJPAC/2018/41446
The extraction and characterization of both cold press and hexane solvent extracted Moringa oleifera oil found in North central (Makurdi, Benue State) Ecological Zone of Nigeria has been carried out. The moringa seed was milled into flour and then divided into two portions. The f...
Open access
Research Article10.9734/IRJPAC/2018/40938
In order to study the relationship between inhibitory concentration and the molecular structures of hydroxamic acids, a Quantitative Structure Activity Relationship (QSAR) study is applied to a set of 31 histone deacetylase inhibitors (HDACi). This study is performed by using the...
Open access
Research Article10.9734/IRJPAC/2018/40895
N-(di (pyridin-2-yl) carbamothioyl)-3-nitrobenzamide (L1) and N-(di(pyridin-2-yl) carbamothioyl)-4-nitrobenzamide (L2)) and their copper (II), nickel (II), cobalt (II) and zinc (II) complexes have been synthesized, characterized and tested for antibacterial activity. The ligands...
Open access
Research Article10.9734/IRJPAC/2018/40567
This article presents the first example of sequentially reported template removal procedure in molecularly imprinted polymers (MIPs) using UV-spectrophotometer. Polymerization was achieved in a glass tube containing 1,4-dihydroxybenzene (DHB) template molecule, methacrylic acid (...
Open access
Research Article10.9734/IRJPAC/2018/38586
The molal solubility, density and refractive index of DL-Methionine (as a nonpolar neutral amino acid) and L-Lysine (as polar basic amino acid) in water–methanol and water–ethanol mixed solvents with alcohol mole fractions (0.0, 0.10, 0.30, 0.50, 0.70, 0.90, and 1.0, by volume) a...
Open access
Research Article10.9734/IRJPAC/2018/40184