Introduction: Tuberculosis (TB) is one of the leading cause of death among infectious diseases. The dual burden of TB and diabetes mellitus (DM) is a major economic and health concern. Anti-TB therapy may predispose patients to develop adverse drug reaction (ADR). The effect of D...
Open access
Research Article10.9734/jamps/2020/v22i730183
Aim: Assess the effect of tartrazine azo dye on atherogenic indices and markers of cardiac injury in albino rats. Study Design: A total number of 63 rats were used for the study. The study was divided into two phases, 1 and 2, which lasted for 30 and 60 days respectively. Phase 1...
Open access
Research Article10.9734/jamps/2020/v22i630179
Background: Imaging techniques are providing physicians an opportunity to ensure more accurate diagnostics. While MRI and CT are the gold standard diagnostic tools, they are not utilized as primary diagnostic tools due to their size, immobility, and exposure to radiation. It is n...
Open access
Research Article10.9734/jamps/2020/v22i630178
Background/Objective: Dolutegravir-based highly active antiretroviral therapy (DTG-HAART) is the preferred regimen in the management of HIV/AIDS. However, the reproductive and oxidative stress toxicity of DTG-HAART is unknown. This study was designed to investigate the reproduct...
Open access
Research Article10.9734/jamps/2020/v22i630177
Ugochukwu Samuel Aguwa, Okeke Somadina Nnamdi, Ezejindu Darmian Nnabuihe, Eze Chinyere Elizabeth, Azurunwa Ogechi, Obinwa Benedict Nzube, Ovie Ogbo. Felix, Obi Kelvin Chukwuemeka, Onwuelingo Sopuru, Okonkwo David, Doris Ogbuokiri & Okeke Chijioke·Journal of Advances in Medical and Pharmaceutical Sciences·2020
Chloroform inhalation is a common method of rodent euthanasia in Nigeria for research purposes. This work is designed to evaluate the consequence of this method of sacrifice on the cerebellum and hippocampus of Wistar rats. Twenty male Wistar rats weighing between 160 and 180 wer...
Open access
Research Article10.9734/jamps/2020/v22i630176
Aim: Evaluate the protective effects of palm oil on renal parameters after dichlorvos toxicity in albino rats. Study Design and Methodology: The study consisted of 3 phases: The acute study which lasted for 24 hours, the sub-acute study which lasted for 14 days and the sub chroni...
Open access
Research Article10.9734/jamps/2020/v22i630175
Background and Objective: Modified-release tablet of theophylline that can increase its usefulness despite narrow therapeutic index and short half-life, is being formulated. However, the rate and extent of release of a sustained-release delivery system can be affected by some fac...
Open access
Research Article10.9734/jamps/2020/v22i530173
Background: One of the consequences of increasing urbanization is that many people eat processed foods that contain various chemical substances applied as additives. Some of them may have the ability to suppress male fertility. Aims: To determine the effects of sodium benzoate (N...
Open access
Research Article10.9734/jamps/2020/v22i530174
Microbiome that reside in the human gut are key contributors to host metabolism and are considered potential sources of novel therapeutics in metabolic disorders. This review discusses the role of gut microbiome in the pathogenesis of obesity, type 2 diabetes mellitus (T2DM), chr...
Open access
Research Article10.9734/jamps/2020/v22i530171
Lead a free-radical generating agent is a multi-systemic toxicant which affects major body systems especially the hepatic axis. Several natural products rich in antioxidant agents have been used to ameliorate lead toxicity. Vitamin C present abundantly in palm wine has been noted...
Open access
Research Article10.9734/jamps/2020/v22i530169