Typhoid fever is an essential communicable disease that is endemic in developing countries characterised by poor water supply, sanitary conditions and increasing population. Vaccination with the Salmonella typhi (ST) vaccine is an effective control measure. The two currently lice...
Open access
Research Article10.9734/JAMPS/2018/41329
Objective: To investigate the hypoglycemic activity of both ethanol extract Strophanthus hispidus root (EESHR) and chloroform extract Strophanthus hispidus root (CESHR) respectively. Methods: Both ethanol extract Strophanthus. hispidus root and chloroform extract Strophanthus. hi...
Open access
Research Article10.9734/JAMPS/2018/40393
Objectives: Studies have shown that both physical exercise and singing have beneficial medical effects on the cardiopulmonary functions of humans in health and disease conditions, but it is not yet known whether physical exercise or singing is more effective in producing these be...
Open access
Research Article10.9734/JAMPS/2018/40220
Aims: Currently there is enormous demand for skin-lightening agents, creating a quest for identification of new substances. Tyrosinase has become the main drug target for reducing skin pigmentation. The objective of this study was to detect tyrosinase inhibitory effects of eight...
Open access
Research Article10.9734/JAMPS/2018/40775
Quantitative structure-activity relationship (QSAR) models were combined with density functional computations and used to predict anti-fungi activities in a series of coumarin derivatives. Essential descriptors employed in this study were chosen based on the use of the Genetic Fu...
Open access
Research Article10.9734/JAMPS/2018/22801
Aim: The aim of this study was to implement an in silico bioinformatics analysis for clinically observed missense variants in human DPYD gene to investigate the effect these variants on Dihydropyrimidine dehydrogenase enzyme 's structure and function. Methods: The human DPYD gene...
Open access
Research Article10.9734/JAMPS/2018/40300
Aim: This study was carried out to investigate the effect of captopril on serum liver enzymes (AST, ALT, and ALP), total serum protein and kidney function parameters such as electrolytes (HCO3-, Cl-, Na+, and K+), urea and creatinine in Plasmodium berghei-infected mice. Methodol...
Open access
Research Article10.9734/JAMPS/2018/40599
Background: The increase in consumption of industrial processed food, economic instability consequent to global economic recession; job losses; increase incidence of diabetes and chronic kidney disease; increase steroids use; dyslipidemia; and obesity has been implicated in the g...
Open access
Research Article10.9734/JAMPS/2018/40194
Aims: To determine the influence of Aegopodium podagraria L. aerial part extract on the function of the kidney and the metabolic processes in rats receiving hydrochlorothiazide (HCTZ, 80 mg/kg). Study Design: The rats were randomly distributed to five groups: Group I: int...
Open access
Research Article10.9734/JAMPS/2018/40313
Aims: To determine the phytochemical constituents and antibacterial potential of Cynodon dactylon leaf extracts against Escherichia coli. Study Design: Experimental short-term prospective study. Place and Duration of Study: The study was conducted in Kampala International Univers...
Open access
Research Article10.9734/JAMPS/2018/39990