Background: Triple-negative breast cancer (TNBC) remains a clinically challenging breast cancer subtype, motivating the investigation of repurposed compounds and rational combinations. Metformin and caffeine affect distinct cellular processes, but their quantitative interaction i...
Open access
Research Article10.9734/jcti/2026/v16i3371
Vascular leiomyoma, also known as angioleiomyoma, is a rare benign soft-tissue tumour arising from vascular smooth muscle. Deep-seated lesions in the popliteal fossa with major peripheral nerve involvement may create substantial diagnostic and surgical challenges. A 48-year-old w...
Open access
Research Article10.9734/jcti/2026/v16i3370
Background: Prostate cancer remains a leading cause of cancer mortality among men in Ghana and across sub-Saharan Africa, with many patients presenting at advanced disease stages where survival outcomes are influenced by disease progression, treatment failure, comorbidities, and...
Open access
Research Article10.9734/jcti/2026/v16i3369
Major and extended hepatectomy remains the principal curative treatment for many primary and secondary hepatic malignancies, yet an inadequate future liver remnant (FLR) continues to preclude resection in a substantial proportion of patients and is the dominant determinant of pos...
Open access
Research Article10.9734/jcti/2026/v16i3368
Prostate cancer risk stratification in low-resource clinical settings requires survival-prediction tools that address violations of the proportional hazards assumption, unobserved patient heterogeneity, and nonlinear covariate interactions that classical regression frameworks can...
Open access
Research Article10.9734/jcti/2026/v16i3367
T lymphocytes are central effectors of tumour immunosurveillance and the principal cellular targets of several successful cancer immunotherapies. Their activity in solid tumours is nevertheless constrained by defective priming, exclusion from tumour nests, suppressive myeloid and...
Open access
Research Article10.9734/jcti/2026/v16i3365
Jacques Forwah Ndeh, Edung Emen Samuel, Ofonime Benjamin Essien, Bassey Okon Bassey, Moday Agaei Onovoh, Oke Opeoluwa Oluwaseun, Rukayat Olawumi Olabiyi, Diderot Tiemen Charles, Joy Samuel-Nwadike, Ewa Anthony Obi, Idiege Idiege Omang, Adebayo Adeoye, Chinedum Sam Iheukwumere, Ayobami Olukayode Alalade, Olasunbo Oluwaseun Oyedepo, Gbeminiyi Ebenezer Adekanmbi, Eguakun Eseosa Collins, Adenowo Adegbenga Adeseye, Aleka Joy Omari, Olaleke Ajayi, Isu-Egwu Stella Nnenna, Funsho Jacob Akande, Ilevbare Martina Olohirere, Zahra Aliyu, Akaba Kingsley Onoridea, Nnaji Chimuanya Joseph, Immaculate Ihuoma Ekeagba, Ushie Godwin Abua & Abeshi Sylvester Etenikang·Journal of Cancer and Tumor International·2026
Background: Multiple myeloma (MM) is a complex and multifaceted hematological malignancy characterized by clonal proliferation of plasma cells in the bone marrow. This process may lead to bone destruction, anemia, hypercalcemia, renal impairment, variable relapsing and refractory...
Open access
Research Article10.9734/jcti/2026/v16i3366
Cancer treatment has advanced substantially with the development of molecularly targeted and immune-based approaches that aim to improve therapeutic selectivity and reduce treatment-related toxicity. This review summarises selected emerging technologies in cancer treatment, inclu...
Open access
Research Article10.9734/jcti/2026/v16i3364
Background: Chimeric antigen receptor T-cell (CAR T-cell) therapy has revolutionised cancer treatment, particularly for relapsed or refractory haematological malignancies. However, treatment-related toxicities, including tumour lysis syndrome (TLS), remain a significant concern....
Open access
Research Article10.9734/jcti/2026/v16i3363
Aim: This study assessed the epidemiological profile, treatment modalities, and treatment outcomes of childhood malignancies managed at Korle Bu Teaching Hospital, Ghana, from 2019 to 2023. Study Design: A retrospective cross-sectional study was conducted. Place and Duration of S...
Open access
Research Article10.9734/jcti/2026/v16i3362