Objective: The aim of the present study was to compare the effect of creatine 2% and 5% supplementation with resistance training on the levels of renin and aldosterone Methods: The 60 Wistar rats were randomly assigned to six groups (resistance training, creatine 2% and creatine...
Open access
Research Article10.9734/JPRI/2017/36504
Purpose: To investigate gene expression profile changes in triple negative breast cancer cells (MDA-MB-231) treated with afatinib. Methods: Differential expression of 84 genes commonly involved in breast cancer carcinogenesis was examined in MDA-MB-231 cells treated with afatinib...
Open access
Research Article10.9734/JPRI/2017/36948
Sources and processing techniques could affect performance of Microcrystalline Cellulose (MCC). This study therefore evaluated the suitability of some agricultural wastes as novel sources of MCC; Sorghum Bicolour and Andropogon gayanus. The physics of compaction of the new grades...
Open access
Research Article10.9734/JPRI/2017/37055
Aims: To find evidence that the immune response modifies behavior by regulating sex hormones. Study Design: Experimental transversal case control study and longitudinal experimental case control study. Place and Duration of Study: Biochemistry and Molecular Biology Chair, School...
Open access
Research Article10.9734/JPRI/2017/35335
Sanjay Kumar, Vijaya G. Tirunagaru, Jennifer Ariazi, Amit Awasthi, Venkatesh Babu Jayaraman, Premkumar Arumugam, Mahesh Yanamandra, Sayan Mitra, Sudhir Tiwari, Raghuram S. Tangirala, Thilo Werner, Douglas Thomson, Giovanna Bergamini & Mui Cheung·Journal of Pharmaceutical Research International·2017
Background and Aim: Acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is a key enzyme catalyzing the final step of triglyceride (TG) synthesis and is implicated in fat absorption and disposition. However, development of several DGAT1 inhibitors has been hampered due to unaccepta...
Open access
Research Article10.9734/JPRI/2017/36835
Aims: Nanoparticle composites are a recent research hotspot, with the potential to be drug-delivery vehicles for more efficient treatment of malignant cancerous tumors. However, as this is a relatively new field, the safety of these nanoparticles is of concern. In this study, we...
Open access
Research Article10.9734/JPRI/2017/36154
Aim: The aim of this study was to improve solubility and dissolution characteristics of Ibuprofen using granulated fumed silica (Aeroperl®300) as a carrier. Methods: Ibuprofen-silica complex was prepared by solvent evaporation technique using ethanol as the solvent. Formulation I...
Open access
Research Article10.9734/JPRI/2017/36872
Objective: The objective of this work was the screening of different phytoconstituents and invitro antioxidant potential and α-glucosidase inhibitory activity of aerial parts of Fagopyrum tataricum. Methods: Preliminary phytochemical screening was performed by using standard prot...
Open access
Research Article10.9734/JPRI/2017/36067
Md. Najem Uddin, Md. Hafizur Rahman, Md. Mehedi Hasan, Md. Nazmul Islam, Md. Bokhtear Sarkar, Md. Rafiul Islam, S. M. Abdul Barik & Md. Nazmul Sardar·Journal of Pharmaceutical Research International·2017
Aims: It is a base line survey to find the reason behind the misuse of antibiotic in Bangladesh. Study Design: Questionnaires were supplied to corresponded persons to collect information from patient, doctors & pharmacy shop from seven region of Bangladesh. The data was analy...
Open access
Research Article10.9734/JPRI/2017/36672
Objective: To evaluate histomorphological, toxicological and antimicrobial activities of ethanolic extract of Calliandra portoricensis root in rodents. Introduction: C. portoricensis is usually administered for a lengthy period in treating diseases like dysmenorrheal, rheumatism...
Open access
Research Article10.9734/JPRI/2017/34701