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Journal of Pharmaceutical Research International

· ISSN (electronic) 2456-9119

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175

Articles indexed

0

2026 articles

175

Open access

304

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Articles (175)

Development and Validation of New Analytical Method for the Determination of Particle Size Distribution of Metformin Hydrochloride Using Laser Based Particle Size Analyzer

Amit Gosar, Shivaji Folane, Sanjay Pawar, Mithun Gharat, Amit Lalge & Shivaji Jadhav · Journal of Pharmaceutical Research International · 2017

Metformin Hydrochloride has characteristic nature of lump formation and determination of particle size with reproducible result is difficult and particle size determination method is not reported in literature. Hence novel rugged and reproducible method has been developed for the...

Open access Research Article 10.9734/JPRI/2017/33911

Efficacy and Safety of Reimbursed Orphan Medicines in Bulgaria – Systematic Review and Meta-analysis (Part I)

Maria Kamusheva, Konstantin Mitov, Miglena Doneva, Assena Stoimenova, Maria Dimitrova & Guenka Petrova · Journal of Pharmaceutical Research International · 2017

Background: To make reimbursement decisions for orphan medicines the regulators need robust evidences for their efficacy and safety provided by systematic reviews and meta-analyses. The goal of the current study is to evaluate the efficacy and safety of orphan medicines included...

Open access Research Article 10.9734/JPRI/2017/34031

Neonatal Effects after Selective Serotonin Reuptake Inhibitors and Benzodiazepines Administration during Pregnancy

Georgios Eleftheriou, Fiocchi Roberto, Butera Raffaella, Giampreti Andrea, Mangili Giovanna & Molinaro Delfina · Journal of Pharmaceutical Research International · 2017

Aims: To evaluate whether the co-administration of benzodiazepines (BDZ) and selective serotonin and serotonin/norepinephrine reuptake inhibitors (SSRI/SNRI) during pregnancy is associated with an increased risk of abstinence symptoms in the newborns. Methods: Twenty six neonates...

Open access Research Article 10.9734/JPRI/2017/34620

A Model to Determine Effective Factors on Pharmacy Major Selection (A Case Study: Students of Zabol University of Medical Sciences)

Mahdi Eydi, Zahra Moradi, Reza Randian, Ali Rahdari & Amin Aliabadi · Journal of Pharmaceutical Research International · 2017

Background: Annually, a large number of students tend to study pharmacy. Students enthusiastically begin their studies; however, they lose their tendency over time. This study addresses motives and effective factors on pharmacy major selection as well as factors which discourage...

Open access Research Article 10.9734/JPRI/2017/31530

Cytotoxicity of Endocytosis and Efflux Inhibitors in the BeWo Cell Line

Mansi Shah, Luke Bourner, Shariq Ali, Sanaalarab Al-Enazy & Erik Rytting · Journal of Pharmaceutical Research International · 2017

Aims: The purpose of this study was to determine the cell viability and cytotoxicity of various endocytosis and efflux inhibitors which can be used to determine transport and uptake mechanisms in the BeWo (b30 clone) human placental trophoblast cell line. Ethanol and dimethylsulf...

Open access Research Article 10.9734/JPRI/2017/34606

Usability of Medicine Package Inserts for Chronic Diseases: A Survey of the Pharmaceutical Market in Jos, Nigeria

B. N. Joseph, U. O. Asiegbu, B. M. Aya, M. N. Nyam, D. M. Umar, N. S. Jimam & M. L. P. Dapar · Journal of Pharmaceutical Research International · 2017

Background: The burden of illness is increasingly tending towards chronic diseases while medication adherence is often unsatisfactory. The patient information leaflet is one model that has the prospect to improve medication adherence. Improving the readability and content based v...

Open access Research Article 10.9734/JPRI/2017/34603

Evaluation of an Undocumented Polyherbal (Faradin®) Used for the Treatment of Sickle Cell Disease in West Africa. Part II: Antibacterial Activity and Synergism

Moji C. Adeyeye, Daniel A. Gbadero, Lawrence O. Farayola, Vicky McKinley, Nikolaos Olalere, Zachary Erlichman, Dami Alabi & Tobi Amosun · Journal of Pharmaceutical Research International · 2017

Aim: This study focused on evaluation of the anti-bacterial effects and synergism of Faradin®), a polyherbal complementary alternative medicine (CAM) and anti-sickling agent. It is used for treatment of sickle cell disease (SCD) and co-morbidities (such as infection and inflammat...

Open access Research Article 10.9734/JPRI/2017/33606

Antimicrobial and Antioxidative Activities in the Stem Extracts of Derris trifoliata, a Mangrove Shrub

Aritra Simlai, Anjali Gangwar, Sarthaki Avinash Ghonge & Amit Roy · Journal of Pharmaceutical Research International · 2017

Aims: An in-depth study on the phytochemical contents, antimicrobial and antioxidative activities of stem tissue of Derris trifoliata Lour. (Fabaceae), a mangrove shrub from Sundarban estuary, India. Methodology: Phytochemical analyses were carried out using established methods f...

Open access Research Article 10.9734/JPRI/2017/34455

Public Knowledge and Awareness about Gout: A Cross-sectional Study in Qatar

Intithar Mohammed M. Alshammari & Md. Ali Mujtaba · Journal of Pharmaceutical Research International · 2017

Background: The prevalence of hyperuricemia and gout had shown an increasing trend all over the world including in developing countries. The patients may receive very little education on the dietary and lifestyle factors associated with gout.  Objective of the Study: Assess knowl...

Open access Research Article 10.9734/JPRI/2017/34375

Prophylactic and Protective Activity of Crude and Methanolic Extract of Punica granatum Peel against Gentamicin Induced Nephrotoxicity

Mobasher Ahmad, Rizwana Wazir, Rukhsana Anwar, Sairah Hafeez Kamran, Afroze Mobasher & Usman Akhtar · Journal of Pharmaceutical Research International · 2017

The aim of the current study was to investigate the nephroprotective effect of Punica granatum peel (pomegranate) against gentamicin induced nephrotoxicity. The crude pomegranate peel (600 mg/kg) and methanolic pomegranate extract (600 mg/kg) for 7 days showed significant (p<0...

Open access Research Article 10.9734/JPRI/2017/34616