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Organics

Published by MDPI AG · ISSN (electronic) 2673-401X

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94

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2026 articles

94

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Articles (94)

Consecutive Four-Component Coupling-Addition Aza-Anellation Pictet–Spengler Synthesis of Tetrahydro-β-Carbolines: An Optimized Michael Addition and Computational Study on the Aza-Anellation Step

Kai Ries, Françoise A. Aouane & Thomas J. J. Müller · Organics · 2023

Starting from acid chlorides, alkynes, tryptamines, and acryloyl chloride, 21 densely substituted tetrahydro-β-carbolines were prepared in a four-component, one-pot reaction. In this study, the aza-Michael addition step to generate intermediate enaminones was optimized in the pre...

Open access Research Article 10.3390/org4030025

Structural and Dynamic Behaviour of Heterocycles Derived from Ethylenediamines with Formaldehyde: 1,3,5-Triazinanes and Bis(imidazolidinyl)methanes

Raúl Colorado-Peralta, Sonia Araceli Sánchez-Ruiz & Angelina Flores-Parra · Organics · 2023

Formaldehyde is a simple chemical compound that is used as a building block in obtaining a wide range of products. The versatility of formaldehyde in chemical synthesis becomes evident when it is reacted with N-alkylethylenediamines. Therefore, this paper reports the structure an...

Open access Research Article 10.3390/org4020024

Palladium Catalyzed Allylic C-H Oxidation Enabled by Bicyclic Sulfoxide Ligands

Yuming Wen, Jianfeng Zheng, Alex H. Evans & Qiang Zhang · Organics · 2023

The activation of C-H bonds is a potent tool for modifying molecular structures in chemistry. This article details the steps involved in a novel ligand bearing a bicyclic [3.3.1]-nonane framework and bissulfoxide moiety. A palladium catalyzed allylic C-H oxidation method enables...

Open access Research Article 10.3390/org4020023

Hydrogen-Bonding Secondary Coordination Sphere Effect on CO2 Reduction

Anamarija Briš & Davor Margetić · Organics · 2023

Great efforts of the scientific community are focused on the development of catalysts for the reduction of carbon dioxide (CO2) to useful molecules such as carbon monoxide, formic acid, methanol, ethanol, methane, ethylene, or acetate. Various metal porphyrin complexes were synth...

Open access Research Article 10.3390/org4020022

The Use of a Natural Polysaccharide as a Solidifying Agent and Color-Fixing Agent on Modern Paper and Historical Materials

Lucia Emanuele, Tanja Dujaković, Graziella Roselli, Simone Campanelli & Giulia Bellesi · Organics · 2023

This article presents results on the use of a new material as a solidifying agent and/or color-fixing agent. A special polysaccharide material extracted from the prickly pear cactus (Opuntia ficus indica) was tested on historical materials and modern papers. An old book from the...

Open access Research Article 10.3390/org4020021

Facile Photochemical/Thermal Assisted Hydration of Alkynes Catalysed under Aqueous Media by a Chalcogen Stabilized, Robust, Economical, and Reusable Fe3Se2(CO)9 Cluster

Munsaf Ali, Avinash K. Srivastava, Nitinkumar Satyadev Upadhyay, Naveen Satrawala & Raj K. Joshi · Organics · 2023

In this report, the catalytic potential of chalcogen-stabilized iron carbonyl clusters [Fe3E2(CO)9 (E = S, Se, Te)] for the photolytic hydration of alkynes has been explored. The iron chalcogenide clusters bring excellent transformations of terminal and internal alkynes to their...

Open access Research Article 10.3390/org4020020

A Novel Class of Functionally Tuneable Star-Shaped Molecules for Interaction with Multiple Proteins

Debashis Barik, Geethanjali Anand, Subba Rao Cheekatla & Mintu Porel · Organics · 2023

Molecules with tuneable properties are well known for their applications in the material and bio-medical fields; nevertheless, the structural and functional tunability makes them more significant in diverse applications. Herein, we designed and synthesized a novel class of star-s...

Open access Research Article 10.3390/org4020018

The Regio- and Stereoselective Synthesis of 1,4-Diarylbut-1-en-3-ynes Having Aryl Groups at the Mutual Syn Positions

Szymon Rogalski, Natalia Szymaszek & Cezary Pietraszuk · Organics · 2023

(E)-1-aryl-2,4-bis(trimethylsilyl)but-1-en-3-ynes readily undergo protodesilylation and subsequent aerobic, copper-free Sonogashira cross-coupling with aryl halides to form (E)-1,4-diaryl-2-(trimethylsilyl)but-1-en-3-ynes. The proposed one-pot, two-step approach allows access to...

Open access Research Article 10.3390/org4020017

Computational Modeling of the Feasibility of Substituted [1.1.1]Propellane Formation from Anionic Bridgehead Bromide Precursors

Katherine E. Gates, Caitlin Herring, Andrew T. Lumpkin, Robert J. Maraski, Elizabeth G. Perry, Madelen G. Prado, Sarah L. Quigley, Jazmine V. Ridlehoover, Edith Salazar, Kynslei Sims, Kaitlin R. Stephenson, Emma A. Stewart, Mackenzie E. Sullivan, James R. Tucker & Gary W. Breton · Organics · 2023

[1.1.1]Propellane, a compound whose structure includes two saturated carbons in which all four bonds are directed into a single hemisphere, is of theoretical interest, but has also seen recent practical applications. Mono-, di-, and trisubstituted derivatives of this propellane (...

Open access Research Article 10.3390/org4020016