The Etiology and Diagnosis of Primary Myelofibrosis: Case Study
M. B. Indu, Saima Khan, Brijesh Sharma, P. Lalita Jyotsana
Asian Journal of Case Reports in Medicine and Health · pp. 35–39 · Published 17 Jun 2022
Abstract
Primary myelofibrosis is a myeloproliferative neoplasm. It is the rarest among the group of myeloproliferative neoplasms and the incidence is 0.1-1 per 1,00,000 per year. This is characterised by the replacement of normal marrow by fibrous tissue. Patients may present with hepatosplenomegaly due to extramedullary erythropoiesis. A high index of suspicion is needed to diagnose the same. This study describes a case that was diagnosed to have myelofibrosis when he presented with splenomegaly as a main symptom.
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