Complex Central Odontogenic Fibroma: A Literature Update on a Clinical Case

Abstract

Central odontogenic ossifying odontogenic fibroma is a low-incidence tumor produced by connective tissue surrounding the dental organs. It was first described in 1967 by the Swedish pathologist Christer Lindahl. In 2017, the World Health Organization classified it within the benign odontogenic ectomesenchymal tumors with or without inclusion of odontogenic epithelium. It has been associated with an alteration in chromosome 2, in the short arm region (2p16). The most commonly identified chromosomal abnormality is the translocation t(2;11) (q31;p13) involving chromosomes 2 and 11. A 52-year-old female patient was referred from a private consultation for presenting an asymptomatic depression in the right premaxillary region. She had no significant medical history relevant to her current condition. Physical examination revealed a melanocytic lesion on the right cheek with irregular borders and a café-au-lait color, measuring 1 cm in diameter. Intraoral examination revealed a mesial rotation of tooth 11. A cavity is observed in the mucosa of the palatal rugae in the radicular direction of tooth 12, with a bluish-white coloration, normothermic, with a depression measuring approximately 4x6x2 mm