Comparative Evaluation of Probiotic Strips and Tetracycline Fibres as Adjuncts to Non-surgical Periodontal Therapy: A Case Series

Abstract

Introduction: Probiotics have gained attention in periodontal therapy due to their potential to modulate the oral microbiota and improve periodontal health. This study wants to evaluate the effectiveness of probiotic strips VS tetracycline fibres in non-surgical pocket reduction in periodontitis patients. Objectives: The primary objective is to assess the reduction in pocket depth following the use of probiotic strips compared to a tetracycline fibres. Secondary objectives include evaluating changes in clinical attachment level, bleeding on probing in the periodontal pockets. Case Presentation: A split-mouth design was employed, with 10 participants receiving both interventions in different quadrants of the mouth. Pocket depths was measured at baseline and after treatment with either probiotic strips or tetracycline fibres. The primary outcome measure was the reduction in pocket depth following treatment. Secondary outcomes, including changes in clinical attachment level and bleeding on probing, was also be assessed. Discussion: The study results will be presented in terms of changes in probing pocket depth, clinical attachment level, bleeding on probing, between the site A and site B. Statistical analysis will be conducted to determine the significance of these changes. Both probiotic strips and tetracycline fibres showed comparable improvements in pocket depth, CAL, and bleeding on probing. These findings align with previous reports on probiotics as host-modulating agents and tetracycline fibre therapy. The study provides valuable insights into adjunctive therapies for periodontal disease. Conclusion: The findings of this study provided valuable insights into the effectiveness of probiotic strips and tetracycline fibres in non-surgical pocket reduction in patients with periodontal disease. If proven effective, it could serve as a promising adjunctive therapy in periodontal treatment protocols.